We found out that our NIAID Flu Systems Vaccinology R01 (Role: MPI, other PIs: Alcorn, Singh, Zimmerman) will be funded.
We participated in a Pitt-Case Western CFAR application that was funded.
Our CIHR grant (Role: co-I, PI: Konvalinka) was funded.
We published a manuscript in Cell Reports Medicine demonstrating how integrating bulk RNA-seq data with protein networks can uncover signatures underlying rejection in pediatric liver transplantation. (link)
Our DoD grant (Role: co-I, PIs: Lafyatis and Singh) looking at multi-omic signatures of scleroderma disease severity was funded.
Our Essential Regression manuscript was published in Patterns. (link)
Javad Rahimikollu from the CPCB program joined the lab as a graduate student (PhD)
Three new graduate students (PhD) joined the lab - Swapnil Keshari from the CPCB program, Prabal Chhibbar and Trirupa Chakraborty from the ISB program joined the lab after rotations.
A NIAID R01 we participated in (Role: co-I, PIs: Rinaldo and Mailliard) looking at COVID-19 vaccine responses in HIV individuals was funded.
We received a 5-year NHGRI U01 1U01HG012041-01 (Role: MPI, Other PIs: Singh, Sahni). Link on NIH Reporter - https://reporter.nih.gov/search/j2KmbxuMYkium4-hI-96ag/project-details/10297231
We received a 5-year NIAID New Innovator DP2 Award 1DP2AI164325-01 (Role: PI). Link on NIH Reporter - https://reporter.nih.gov/search/j2KmbxuMYkium4-hI-96ag/project-details/10295268
Eunseo Song joins the lab as an undergraduate (CMU Computational Biology) researcher.
Rucha Khopkar joins the lab as a Master's Student.
A NIDDK dkNET New Investigator Pilot Program in Bioinformatics grant that we participated in has been funded (Role: co-I, PI: Joglekar).
Hanxi Xiao, who did her Master's thesis in the lab will continue in the lab as a PhD student in the CMU-Pitt Program in Computational Biology.
We contributed to Mechanisms of impaired lung development and ciliation in Mannosidase-1-alpha-2 (Man1a2) mutants in Frontiers in Physiology
Jacob Berkowitz joins the lab as an undergraduate (Pitt Statistics) researcher.
Jishnu gave a talk at the 2021 Cold Spring Harbor Systems Immunology Meeting
A Department of Defense Idea Development Award grant that we participated in has been funded (Role: co-I, PI: Lafyatis).
Jishnu gave a talk at the 2021 Cold Spring Harbor Networks Meeting
We published Mining for humoral correlates of HIV control and latent reservoir size in PLoS pathogens
We welcome Woo Yong "Noah" Chang, who is going to work with us as a Master's Student.
We welcome Hanxi Xiao, who is going to work with us as a Master's Student.
We contributed to Extracellular Matrix Injury of Kidney Allografts in Antibody-Mediated Rejection: A Proteomics Study, which was published in the Journal of the American Society of Nephrology
Sophia Hu (CMU-Pitt Program in Computational Biology) does a rotation in the lab.
We are now supported by a Collaborative Research Agreement with the University of Brussels Center for Research In Immunology (Role: PI)!
We published Mapping functional humoral correlates of protection against malaria challenge following RTS, S/AS01 vaccination in Science Translational Medicine
We received a pilot Covid-19 grant from the UPMC-ITTC (Role: PI)!
We welcome Kiran Nazarali, who is going to work with us as a High School Student.
We received a PACER (Pittsburgh Autoimmunity Center for Excellence in Research) grant (Role: PI)!
We welcome Syed Rahman, who is going to work with us as a Post-Doctoral Fellow.
We contributed to Latency reversal agents modulate HIV antigen processing and presentation to CD8 T cells, which was published in PLoS pathogens
We contributed to Epigenetic basis for monocyte dysfunction in patients with severe alcoholic hepatitis, which was published in the Journal of Hepatology
Roshni Bhatt (CMU-Pitt Program in Computational Biology) does a rotation in the lab.
We published Antibody Fc Glycosylation Discriminates Between Latent and Active Tuberculosis in The Journal of Infectious Diseases
The Das Systems Immunology Lab is now supported by Center for Systems Immunology Startup Funds!
The lab is now open! We look forward to exciting science in the future!